Nilathak's Temple a.k.a. Pindle Run (Act 5)In Act 5, players don't need to travel far into Mount Arreat to get a ideal farming spot D2R Ladder Items. It's the place of Harrogath already is one of the best grinding locations during the course of the game. Nilathak's Temple is the best place to go, where players don't have to clear the entire area clean.
The threat they are after is Pindleskin who's waiting for them at the front of the gate. In the past, Pindleskin's drop rate was reduced however, he's still able to drop some very high treasure class items. Take note that players with a low level of life (less less than 1000) could be killed by Pindleskin in a few swings.
Frigid Highlands (Act 5)Although this universe is mostly created randomly The boss always appears to be in the same position every time. Eldritch and his gang are typical super uniques that remain just north of the routepoint every time, which makes Eldritch a predictable target and the easiest attack.
Not all classes are equipped to win the game and all players can take on the Frigid Highlands without much difficulty. When you play Act 5 on higher difficulties it's nearly impossible to find an area where immunity rules aren't all over area Diablo II Resurrected Items, but the frigid Highlands is one of the areas that anybody can reasonably cultivate.