One of the drugs used for impotence is Penegra . This tablet is very effective in treating erectile dysfunction. If you want to spend some quality time with your wife or girlfriend, take it 30 minutes before you engage in sexual activity. The active ingredient in Penegra, increases blood flow to men's penile tissue. The effects of this medication take 4 to 6 hours to kick in. Do not chew or break this medication. Take it orally with water. Follow your doctor's instructions. Do not take this medication with fattening foods or alcoholic drinks. This medication is for use by men 18 years of age and older.