Sildenafil works by blocking the enzyme phosphodiesterase type 5 (PDE5). This increases levels of cyclic GMP, which relaxes the smooth muscles in the blood vessels of the penis, allowing increased blood flow and facilitating an erection.Silagra 50 mg is a medication used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate, which is the same active ingredient found in Viagra.

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